THE C-REACTIVE PROTEIN ACCORDING TO LUNG INVOLVEMENT OF COVID-19 PATIENTS AT VERY HIGH ALTITUDE

Proteína C reactiva en COVID-19 en alta altitud

Abstract

Introduction

The protein C-reactive is an important immunological marker due to its sensitivity to stimulate inflammation and or infections, it is necessary to study its role in the lung compromise and the evolution of COVID-19 disease. The objective of the present study is to determine the behavior of C-Reactive Protein according to lung involvement, in patients with a positive diagnostic of COVID-19 in the Hospital del Norte in El Alto, from 2021.

Material and method

It is a study which is characterize of observations, explanations, transversal, retrospective, due to a random simple sampling of 196 patients with a diagnosis of pneumonia and a positive RT-PCR test. There was a statistical analysis performed by the test of “chi cuadrado” where the variable depends on a report CORADS (compromise lung) and the independent variable is the protein C-reactive. Therefore, it can be calculate the frequency of variables: sex, age, type of relation between the age, PCR and CORADS and relation between the discharge types.

Results

196 subjects with the diagnostic of pneumonia and a positive RT-PCR were studied. There were found statistically a significance concentration between C-reactive protein and lung compromise (p = 0.000 < 0.05).

Discussion

The present study showed that there is a positive association between C - reactive protein concentrations and lung involvement. In view of the p-value obtained (p=0.01 < α=0.05), the existence of a statistical dependence between pulmonary involvement and the concentrations of C-Reactive protein is evident, the pulmonary involvement reported by the CORAD system varies in relation to the concentration of C-Reactive Protein

Keywords: COVID-19, CRP, CORADS.