Neutrophyl to lymphocyt ratio vs platelets to lymphocyt ratio as inflammatory markers in patients of the Hemodialisis service of Elizabeth Seton Hospital 2017-2018
DOI:
https://doi.org/10.52428/20756208.v17i43.229Keywords:
Inflamattion, Cronic Kidney Disease, NeutrophilesAbstract
Summary:
Introduction
Chronic kidney disease (CKD) is a multifactorial process of a progressive and irreversible nature that frequently leads to a terminal state, increasing cardiovascular mortality, which is why various inflammation markers have been sought the neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) being two easily accessible and low-cost study markers.
Metodology
The main objective is to compare the value as an inflammatory marker of NLR vs PLR. A retrospective, cross-sectional and descriptive research work was carried out, with the objective of comparing the value of the Neutrophil-lymphocyte ratio and the Platelet-Lymphocyte ratio as inflammatory markers in patients of the Hemodialysis Service of Elizabeth Seton Hospital October / 2017-October / 2018. The universe was patients with chronic kidney disease from the Hemodialysis service. The study variables were: Neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, CRP, albumin, hemoglobin, age. The data was collected from the clinical records in a previously defined instrument, and then transcribed into Excel v.15 and imported into SPSS v.22.
Results
In the first measurement, only 4 patients (12.9%) presented a high NLR and 20 patients (64.5%) presented a high PLR and a weak positive relationship (r) was found for both NLR 1 and PLR 1 with the CRP 1 (r=0.205 vs 0.033), with the relationship strength of NLR 1 being greater. In the second measurement, a high NLR was observed in 6 patients (19.4%) and 24 patients (77.4%) presented a PLR high with a strong positive correlation of NLR 2 with CRP 2 (r=0.640) and a moderate strength of correlation of PLR2 with CRP 2 (r=0.391; p<0.05).
Discussion
The results we found were that both NLR and PLR are easy-to-calculate, accessible and low-cost inflammatory markers, which have a strong positive correlation with PCR, however it was not observed that the PLR had a greater positive correlation than the NLR with the PCR, but it was observed that the number of patients with anemia and hypoalbuminemia was higher in the group with altered PLR.
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References
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